Household Air Pollution Intervention Network (HAPIN)

          The HAPIN cohort consists of participants living in rural settings in Puno, in southeastern Peru at the shores of Lake Titicaca at 3,825 meters above sea level. Study participants live in rural villages of the Puno Province, where biomass fuels are the primary source of fuel for cooking.  Using a rolling recruitment process, we are recruiting 800 pregnant women (one per household) and an additional 200 older adult women from the same households who meet inclusion/exclusion criteria. At birth, parents will be approached to consent for their newborn child to participate in the study.

Characteristics of pregnant women enrolled:
·         Aged 18 to 34 years;
·         Less than 20 weeks gestation confirmed by ultrasound
·         Singleton pregnancy
·         No fetal anomalies identified during first ultrasound
·         Usually uses a biomass stove
·         Not currently a smoker
·         No plans* to move out of current household in next 30 months
·         Agrees to participate with informed consent
·         BMI less than or equal to 40 kg/m2

Characteristics of pregnant women enrolled:
·         Aged 35 to 64 years
·         Not currently a smoker
·         Resides in household with participating pregnant woman and has no plans* to move out of current household in next 30 months
·         Agrees to participate with informed consent
·         Does not use anti-hypertensives

Learn more at www.hapintrial.org or at https://clinicaltrials.gov/ct2/show/NCT02944682